Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- distal bone resorption
研究概览
简要总结
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to second molar of the study and control groups after third molar surgical removal.
Sample include of participants who had indication of impacted lower third molars extraction on both sides with symmetrically orientation and same difficult index. All participants had same extraction protocol on both side at Department of Oral surgery, Faculty of Odonto-stomatology, University of Medicine and Pharmacy, Ho Chi Minh City.
Soft tissue healing, periodontal pocket depth and distal bone height were evaluation by an independent investigator.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient over 18 years old.
- •Good general health.
- •Bilateral lower third molars equivalent in inclination and Pell and Gregory's impaction classification (classification II, III and B, C). The assessment of equivalence between two mandibular third molars was determined on the panoramic radiograph.
- •The difference of third molar inclination on both sides not greater than 15 degrees.
- •The patient consented to participate in the study after hearing clearly the explanation of purposes and requirements of the study.
排除标准
- •Patients with any systemic disease contraindicated for surgery.
- •Presence of acute inflammation or infection at third molar areas.
- •Patients refused to participate in the study, did not comply with treatment or did not come to the follow-up examination as required.
- •The difference in surgical time between the two groups was more than 10 minutes.
结局指标
主要结局
distal bone resorption
时间窗: 6th postoperative month
resorption of alveolar bone height distal to second molar
periodontal pocket depth
时间窗: 6rst postoperative month
periodontal pocket depth at distal buccal and distal lingual side of second molar
次要结局
- soft tissue healing index(7th postoperative day)
研究者
Lam Cu Phong
Lecturer
University of Medicine and Pharmacy at Ho Chi Minh City