Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Modified Medical Research Council Scale
研究概览
简要总结
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory breathing exercises compared to expiratory breathing exercises alone will help to improve shortness of breath, respiratory symptoms, breathing function, distance walked, and quality of life in those who are experiencing persistent shortness of breath after having had COVID-19. Measurements will take place at the beginning, 6 weeks, and at 12 weeks in the study.
详细描述
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory muscle strength training exercises as compared to a prior study of expiratory muscle strength training alone is effective in improving dyspnea, respiratory symptoms, quantitative measures of pulmonary function, physical performance, and quality of life in individuals reporting persistent dyspnea post-COVID-19 at baseline, six and twelve weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Self-reported history of a positive COVID-19 diagnosis in the past.
- •Able to walk independently
- •Cognitively intact
- •English-speaking
- •Dyspnea at rest or with activity rated at 3 or greater on the Dyspnea on Exertion scale.
- •May use oxygen.
- •May be taking medications.
排除标准
- •Individuals who are wheelchair bound or who cannot walk independently.
- •Individuals hospitalized for COVID-19 who self-report that they received mechanical ventilation during hospitalization.
结局指标
主要结局
Modified Medical Research Council Scale
时间窗: Baseline, 6-weeks, and 12-week measurements
Scale of 0-4 with 4 being the most severe dyspnea.
COPD Assessment Test
时间窗: Baseline, 6-weeks, and 12-week measurements.
8-item questionnaire with a semantic, 6-point differential scale for each item. Scores range from 0-40 with higher scores indicating more severe respiratory symptoms.
EuroQoL-5 Dimension-5 Level
时间窗: Baseline, 6-weeks, and 12-week measurements.
EuroQoL-5 Dimension-5 Level to evaluate 5 dimensions of quality of life including mobility, self-care, usual activities, discomfort and pain, anxiety, and depression. Each is scored using a 5-point semantic scale.
Forced Expiratory Volume over 1 second (FEV1)
时间窗: Baseline, 6-weeks, and 12-week measurements
Using the Microlife Digital Peak Flow and FEV1 Meter (Clearwater, FL).
Peak Inspiratory Flow
时间窗: Baseline, 6-weeks, and 12-week measurements.
Using the In-Check Peak Inspiratory Flow meter (Granbury, TX).
Thoracic Expansion Measures
时间窗: Baseline, 6-weeks, and 12-week measurements
Gulick tape measure positioned around the participant's chest at the 4th intercostal space. Participant breathes in and out as far as possible and the difference between the 2 values equals thoracic expansion.
Physical Capacity
时间窗: Baseline, 6-weeks, and 12-week measurements.
6 Minute Walk Test following the American Thoracic Society Procedure: 50-meter distance is marked. Participant walks as quickly as possible for 6 minutes. Results recorded in meters. Vital signs and oxygen saturation monitored and recorded.
次要结局
- Feasibility and Acceptability of the Intervention(12-weeks.)