Effect of Topical Tetracycline and Dexamethasone on Periodontal and Pulpal Regeneration of Replanted Avulsed Permanent Teeth: A Long-term Follow-up After 9-16 Years
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Number of teeth with periodontal regeneration
研究概览
简要总结
To evaluate the effect of topical tetracycline and dexamethasone on periodontal and pulpal regeneration of avulsed permanent teeth after an observation period between 9-16 years.
详细描述
Two different medications were applied prior to replantation. A) Topical tetracycline, B) topical dexamethasone. Teeth were splinted using a non-rigid titanium trauma splint for 7-14 days. Endodontic treatment was performed within 1-7 days, except for teeth with an open apex and a short extraoral dry time. All patients received systemic tetracycline for 10 days after accident and were subsequently re-examined.
Follow-up examinations included periodontal examination, percussion, Periotest measurements, pulp sensitivity using CO2 snow, periapical radiograph and intraoral photographs. Additionally a OHIP-14 questionnaire was carried out to determine the oral health-related quality of life.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 6 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Avulsion of a permanent tooth
- •Written informed consent
排除标准
- •Extended dry period of more than 60 minutes
结局指标
主要结局
Number of teeth with periodontal regeneration
时间窗: After a mean observation period of 12.9±2.4 years (one visit only)
Periodontal regeneration was assessed with periodontal examination, percussion, Periotest measurements and periapical radiograph.
Number of teeth with pulpal regeneration
时间窗: After a mean observation period of 12.9±2.4 years (one visit only)
Pulpal regeneration was assessed with periodontal examination, percussion, Periotest measurements, pulp sensitivity using CO2 snow and periapical radiograph.
次要结局
- Number of teeth that survived(After a mean observation period of 12.9±2.4 years (one visit only))
- Number of teeth with open versus closed apex at accident(At baseline)
- Patients satisfaction(After a mean observation period of 12.9±2.4 years (one visit only))