CTRI/2018/03/012603
Not yet recruiting
未知
Study of effect of teneligliptin versus glimepiride on tumor necrosis factor alpha (TNF- α) and high sensitivity C- reactive protein (hs-CRP) in type 2 diabetes mellitus patients treated with metformin. - TNF/CRP
MALEHA BUT0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- MALEHA BUT
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Body mass index (BMI) more than 25 kg/m2
- •2\.All type 2 DM patients with a history of diabetes for the past 1 to 3 years
- •3\.Type 2 diabetics with fasting blood sugar more than 126mg/dl and glycosylated hemoglobin (HbA1c) between 7\.0 to 10\.0 % before enrollment.
- •4\.All type 2 DM patients, who are on stable dose of metformin (up to 2500mg/day) for the past 12 weeks.
- •5\.All patients naive to teneligliptin and glimepiride.
- •6\.All patients willing to give consent to participate in the study.
Exclusion Criteria
- •1\.Uncontrolled hypertension (systolic BP more than or equal to 180 mmHg and diastolic BP more than or equal to 100 mmHg)
- •2\.Uncontrolled diabetes (HbA1c more than or equal to 10\.0 %).
- •3\.Patientâ??s having serum creatinine (SCr) levels more than or equal to 2mg/dL.
- •4\.Patients with hepatic impairment (AST and ALT levels more than or equal to 3 times the upper limit).
- •5\.Serum triglycerides more than or equal to 500mg/dl.
- •6\.Pregnant females and lactating mothers
- •7\.History of hypersensitivity to study drugs.
- •8\.History of taking non steroidal anti\-inflammatory drugs or any other drugs that affect the study parameters.
- •9\.Patients on any other herbal and dietary supplements.
Outcomes
Primary Outcomes
Not specified
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