N-Acetylcysteine and L-carnitine in Pcos

Phase 2

Completed

• Conditions: PCOS
• Interventions: Drug: N-Acetylcysteine; Drug: L-carnitine

• Registration Number: NCT03164421
• Lead Sponsor: Zagazig University

Brief Summary

N-Acetylcysteine and L-carnitine were used in pcos patients

Detailed Description

N-Acetylcysteine was compared to L-carnitine in clomiphene citrate in Pcos women to detect the hormonal and metabolic effect

Study Timeline

• Study Start: 2017-01
• Study First Submitted: 2017-05-21
• Study First Submitted QC: 2017-05-22
• Study First Posted: 2017-05-23
• Status Verified: 2017-06
• Primary Completion: 2018-06
• Study Completion: 2018-07
• Last Update Submitted: 2018-09-16
• Last Update Posted: 2018-09-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 164

Inclusion Criteria

• pco
• infertile

Exclusion Criteria

• no medical disorders
• no hormonal treatment in the previous 3 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
N-Acetylcysteine	N-Acetylcysteine	N-Acetylcysteine used by clomiphene resistant pcos women
L-carnitine	L-carnitine	L-carnitine used by clomiphene resistant pcos women

Primary Outcome Measures

Name	Time	Method
pregnancy rate	3 momths	number of women with clinical pregnancy

Secondary Outcome Measures

Name	Time	Method
abortion rate	3 momths	number of women with abortions
ovulation rate	3 momths	number of women with follicle \>18mm.

Trial Locations

Locations (1)

Zagazig University; 🇪🇬 Zagazig, Egypt