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Clinical Trials/JPRN-UMIN000012752
JPRN-UMIN000012752
Completed
Phase 2

A multicenter phase II trial of everolimus for unresectable pancreatic neuroendocrine carcinoma refractory or intolerant to platinum-based regimen - NECTOR

ational Cancer Center Hospital East0 sites25 target enrollmentJanuary 6, 2014

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
nresectable pancreatic neuroendocrine carcinoma
Sponsor
ational Cancer Center Hospital East
Enrollment
25
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 6, 2014
End Date
January 6, 2019
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
ational Cancer Center Hospital East

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • 1\) NET G1 or G2 by WHO 2010 criteria 2\) Interstitial pneumonia or plumonary fibrosis 3\) Metastasis to the central nervous system 4\) Concomitant malignancy within 3 years 5\) Active infection (exept for hepatitis B or C viral infection) 6\) Active gastrointestinal ulcer 7\) Severe or uncontrollable complications, such as cardiovascular impairment, infection, diabetes mellitus, and pulmonary disease 8\) Severe mental disorder 9\) Continuous administration of steroid or immunosuppressant 10\) Prior treatment of mTOR inhibitor 11\) Pregnant or lactating women and women of childbearing age who were not using effective contraception 12\) Patients who was judged to be inappropriate for this study by each investigators

Outcomes

Primary Outcomes

Not specified

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