The effect of honey and chamomile mouth washes in the prevention of head and neck radiotherapy –induced stomatitis

Recruiting

• Conditions: Cancer - Head and neck; Oral and Gastrointestinal - Inflammatory bowel disease; Head and Neck cancer; stomatitis

• Registration Number: ACTRN12610000847011
• Lead Sponsor: Tehran University of Medical Siences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Participation with a diagnosis of head and neck cancer and willing participate.
-Aged 8 years or more
-Non treat with steroid
-Avoid tobacco, alcohol, smoking, opiate substance

-External beam radiotherapy with dose 180-200 CGY Daily
-Non Leucopenia(White Blood Cell<4000mm^3 )
-Non Leucocytes(White Blood Cell>12000mm^3)
-Non Thrombocytopenia

Exclusion Criteria

- Non Certain systemic condition such as diabetes, Defect in the immune system, Renal disease, Liver disease, Gastrointestinal Disease, Asthma, Allergic
-Allergic to the mouth wash solution
-Temperature>38.5 degrees celius
-Nausea & Vomiting

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decreased risk stomatitis after radiotherapy withWorld Health Organisation ( WHO) scale.<br>WHO scale= grading scale of 0-4 (0, absent; 1, slight pain, erythema; 2, sore defects, can eat solids; 3, very sore defects, requires liquid diet only; 4, alimentation not possible).[Decreased risk of stomatitis on completion of all radiotherapy treatment at 1 day.]

Secondary Outcome Measures

Name	Time	Method
Decreased risk stomatitis after 14 days radiotherapy withWorld Health Organisation ( WHO) scale.<br>WHO scale= grading scale of 0-4 (0, absent; 1, slight pain, erythema; 2, sore defects, can eat solids; 3, very sore defects, requires liquid diet only; 4, alimentation not possible).[Decreased risk of stomatitis on completion of all radiotherapy treatment at 14 days.]