Effects of High-intensity Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke.

Not Applicable

Completed

• Conditions: Stroke
• Interventions: Other: Exercise Therapy; Other: conventional therapy

• Registration Number: NCT04752124
• Lead Sponsor: Government College University Faisalabad

Brief Summary

Stroke is one of the major cause of morbidity and mortality and the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen.

The purpose of this study is to Determine the effect of high intensity speed based treadmill training on Balance, Walking capacity and quality of life in sub-acute stroke.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-07
• Study First Submitted: 2021-02-09
• Study First Submitted QC: 2021-02-09
• Study First Posted: 2021-02-12
• Primary Completion: 2021-02-27
• Status Verified: 2021-03
• Study Completion: 2021-03-15
• Last Update Submitted: 2021-03-15
• Last Update Posted: 2021-03-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• age 40-80 years; first episode of stroke; >4 weeks of stroke onset; hemiparesis resulting from unilateral ischaemic stroke; Ashworth score of 0 or 1, indicating no spasticity or slight spasticity over the affected lower limb, respectively; mini-mental state examination score ≥23; ability to perform independent walking for at least five minutes with or without an assistive device (FAC=3). All patients will be determined to be in stable cardiovascular condition with a low although slightly greater risk for vigorous exercise than for apparently healthy persons (class B according to the American College of Sports Medicine [ACSM]).13

Exclusion Criteria

• Participants will be excluded from the study if they had any of the following: (1) chronic cardiorespiratory or metabolic diseases; (2) severe osteoporosis; and (3) lesions pertaining to the brainstem or cerebellum; (4) having resting blood pressure above 160/100 mmHg even after taking medications; (5) cardiovascular comorbidity (aortic stenosis, depression of ST-segment, heart failure, arrhythmias, unstable angina, hypertrophic cardio-myopathy); (6) transient ischemic attack; (7) by-pass surgery in the recent three months; and (8) other musculoskeletal problems that prevented the participants from doing aerobic activity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
HIIT+CT	conventional therapy	HIIT combined with conventional rehabilitation.
HIIT+CT	Exercise Therapy	HIIT combined with conventional rehabilitation.
Conventional therapy	conventional therapy	Conventional rehabilitation will be provided to this group of patients.

Primary Outcome Measures

Name	Time	Method
6 minute walk test	6 weeks of training	To determine the endurance after stroke

Secondary Outcome Measures

Name	Time	Method
Stroke Impact scale	5 weeks	To measure the impairment and quality of life after stroke. The maximum score is 140.
Berg Balance scale	5 weeks	It is used to measure the Balance and stability of patient. Total score of the scale is 56. A score of \< 45 indicates individuals may be at greater risk of falling.

Trial Locations

Locations (1)

Bin Inam Rehabilitation Center.; 🇵🇰 Faisalābad, Punjab, Pakistan