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临床试验/CTRI/2025/02/081237
CTRI/2025/02/081237尚未招募4 期

Effect of Nitya Virechana with Narayana Churna in the Management of Non-Alcoholic Fatty Liver Disease (NAFLD)

Government Ayurveda College Tripunithura, Ernakulam1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2025年3月8日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
28
试验地点
1
主要终点
Change in the grade

研究概览

简要总结

This trial is conducted to assess the Effect of Nitya Virechana with Narayana Churna  in the Management of Non alcoholic Fatty Liver Disease. During the intervention the participants will be given 12 g Narayana Churna with hot water at bed time for a period of  30 days as Nitya Virechana.The study will be conducted in Government Ayurveda College Hospital, Tripunithura having laboratory and USG facility which makes the study more feasible .The study design is pre and post- study .A sample of 28 will be selected based on inclusion and exclusion  criteria.The subjects will be  administered Narayana churna for the first 10 days  on IP basis and the remaining duration  on OP basis. The assessment of Virechana will be done daily basis.They will be subjected to detailed clinical evaluation and investigation including USG Abdomen, LFT, Lipid profile ,Platelet, Electrolyte, RFT and FBS. Fibrosis score will also be calculated .Elastography will be done for a sub group. USG and Elastography will be done before and after the treatment. All the above blood tests will be checked on 10 th, 20 th ,30 th and 60 th day.  Data collection will be done through case proforma,USG abdomen , blood tests and elastography in a sub  group.Data collected will be statically analysed through appropriate tests and conclusion will be drawn.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
30.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Subject among age group 30-55 who are diagnosed as fatty liver Grade 1and 2, diagnosed by USG and Fibroscan in a sub group at the OPD and IPD of Govt.
  • Ayurveda College Hospital ,Tripunithura.

排除标准

  • 1.Known cases of Major Systemic illness 2.Known cases of Malignancy 3.Known cases of Portal hypertension 4.Known cases of Splenomegaly 5.Pregnant and lactating women 6.Subjects having Mridu koshta.

结局指标

主要结局

Change in the grade

时间窗: 30 days

of fatty liver as observed through USG Abdomen

时间窗: 30 days

次要结局

  • 1. Change in the score(of NAFLD fibrosis score)

研究者

发起方
Government Ayurveda College Tripunithura, Ernakulam
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

DrSheejaS

Govt Ayurveda College Hospital,Tripunithura

研究点 (1)

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