Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery

Completed

• Conditions: Basal Cell Carcinoma; Squamous Cell Carcinoma
• Interventions: Procedure: Blood Draw

• Registration Number: NCT00793169
• Lead Sponsor: Northwestern University

Brief Summary

The primary objective of this study is to (1) determine whether local injection of lidocaine used during Mohs surgery will elevate serum lidocaine concentrations to a level that could cause systemic symptoms and (2) determine whether sustained high levels of serum lidocaine occur after intralesional anesthesia on the face and neck. This study is a cross-sectional study of 10 subjects with basal cell carcinoma or squamous cell carcinoma of the face or neck requiring Mohs micrographic surgery. The study will consist of a brief questionnaire and blood draws during their Moh's surgical procedure.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Study First Submitted: 2008-11-17
• Study First Submitted QC: 2008-11-18
• Study First Posted: 2008-11-19
• Results First Submitted: 2010-09-30
• Results First Submitted QC: 2010-10-29
• Results First Posted: 2010-11-30
• Status Verified: 2021-12
• Last Update Submitted: 2021-12-02
• Last Update Posted: 2021-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
lidocane	Blood Draw	Patients undergoing Mohs micrographic surgery of the face or neck will have their blood drawn before, during, and after the procedure.

Primary Outcome Measures

Name	Time	Method
The Number of Subjects With Detectable Serum Lidocaine Concentrations (<0.1 ug/mL) at Each Blood Draw.	6 hours

Trial Locations

Locations (1)

Northwestern University; 🇺🇸 Chicago, Illinois, United States