Development of a comprehensive gene mutation testing system named Mutation Investigator using the Next-era Sequencer (MINtS)
Not Applicable
- Conditions
- on-small cell lung cancer
- Registration Number
- JPRN-UMIN000015665
- Lead Sponsor
- orth East Japan Study Group (NEJSG)
- Brief Summary
We developed a next-generation sequencer (NGS)-based, multi-gene test named the MINtS for investigating driver mutations in both cytological specimens and snap-frozen tissue samples. The MINtS was used to investigate the EGFR, KRAS, BRAF genes from DNA, and the ERBB2, and the ALK, ROS1, and RET fusion genes from RNA. We focused on high specificity and sensitivity (more than 0.99) and even included samples with a cancer cell content of 1%.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 190
Inclusion Criteria
Not provided
Exclusion Criteria
no exclusion criteria
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method