Benefit of a flash dose of corticosteroids in digestive surgical oncology: a randomized, double blind, placebo-controlled trial

CHU Dijon Bourgogne0 个研究点目标入组 1,200 人开始时间: 2019年3月14日最近更新: 2024年9月2日

试验速览

暂无简介。

•- Age = 18 years
•- Undergoing elective surgery for a digestive cancer (except purely hepatic surgery)
•- Patients operated in a curative intent
•- Patients who had given their written informed consent
•- Patients affiliated to a National health insurance scheme
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•- Emergency surgery
•- Pregnant or breastfeeding women
•- Patients with an ongoing oral treatment by steroids
•- Palliative surgery
•- Exclusive liver surgery
•- Colorectal resection with concomitant hyperthermic intraperitoneal chemotherapy
•- Patient with at least one contra-indication to methylprednisolone treatment :
•* active infection
•* on course viral disease (particularly hepatitis, herpes, chickenpox, herpes zoster
•* uncontrolled psychotic state
•* hypersensitivity to methylprednisolone or to one of its excipient
•- ASA grade >3
•- Persons subject to a measure of legal protection (guardianship, tutorship)
•- Persons subject to a court order
•- Impossibility to sign the informed consent document or to adhere to the medical follow-up of the trial for geographical, social or psychological reasons

发起方

CHU Dijon Bourgogne