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Clinical Trials/NCT01907126
NCT01907126
Completed
N/A

HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence

Brown University3 sites in 1 country42 target enrollmentSeptember 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Unsafe Sex
Sponsor
Brown University
Enrollment
42
Locations
3
Primary Endpoint
Presence of Trichomoniasis
Status
Completed
Last Updated
last year

Overview

Brief Summary

The pilot study aims to conduct a randomized pilot trial in a sample of 40 incarcerated women with lifetime interpersonal violence who are 6-10 weeks away from release to demonstrate the feasibility and acceptability of the proposed recruitment methods and research design, of the intervention training methods, of delivering the enhanced Women's Coop and nutrition control interventions. Per recent guidance from NIMH, the investigators will also examine 95% confidence intervals around differences between the proposed intervention and a dose-matched control condition (Nutrition Program), for the following outcomes through 8 months post prison release: reduced unprotected vaginal or anal sex occasions and fewer cases of vaginal trichomoniasis (primary); reduced interpersonal violence episodes, symptoms of PTSD and depression, and drug using/heavy drinking days (secondary); and increased affect management and social support (including effectiveness in obtaining substance use, mental health treatment and other resources) (tertiary).

Registry
clinicaltrials.gov
Start Date
September 2011
End Date
October 2014
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Jennifer Johnson

Associate Professor (Research)

Brown University

Eligibility Criteria

Inclusion Criteria

  • Females in prison
  • Experienced lifetime interpersonal violence (includes physical or sexual assault or abuse)
  • At least one unprotected sexual occasion with a male partner within the 90 days prior to incarceration
  • Approximately 6-10 weeks before release
  • Expect to be released to locations within RI or MA
  • Exclusion criteria:
  • Cannot complete intake interview due to problems with reality testing, brain impairment, or language barrier

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Presence of Trichomoniasis

Time Frame: Slope over time: Baseline, 2 months after release, 5 months after release, 8 months after release

The investigators will calculate odds ratios and 95% confidence intervals for any positive trichomoniasis test during follow-up using logistic regression, with baseline trichomoniasis status as a covariate. The presence of Trichomoniasis is measured by rapid test.

Treatment Feasibility

Time Frame: 2 months post release

One of the primary goals of a treatment development study is to demonstrate the feasibility of the proposed treatment and of the study and recruitment methods. As a result, the investigators will assess the feasibility of the research procedures by examining study recruitment and refusal rates, participants' willingness to be randomized, follow-up rates, reliability and range of responses to study questionnaires, and success of the interventionist training program

Number of Unprotected Sexual Occasions (USOs; Vaginal and Anal)

Time Frame: Slope over time: Baseline, 2 months after release, 5 months after release, 8 months after release

The investigators will calculate effect sizes and confidence intervals for number of USOs. The number of USOs will be measured by the Timeline Follow Back (TLFB).

Treatment Acceptability

Time Frame: 2 months post release

The investigators will assess the feasibility and acceptability of WPC and NP by examining rates of treatment attendance, rates of treatment completion (attending at least 5 of the 6 scheduled individual sessions) and drop-out, and scores on the End of Treatment Questionnaire. Additionally, they will examine reasons for termination for consistent patterns. Acceptability of both WPC and NP using data from Client Satisfaction Questionnaire and detailed exit interviews will be examined.

Secondary Outcomes

  • PTSD Symptom Severity(Slope over time: Baseline, Pre-release, 2 months after release, 5 months after release, 8 months after release)
  • Interpersonal violence (IPV) episodes(Slope over time: Baseline, 2 months after release, 5 months after release, 8 months after release)
  • Post Release Drug Using/Heavy Drinking Days(Slope over time: 2 months after release, 5 months after release, 8 months after release)
  • Depressive Symptom Severity(Slope over time: Baseline, Pre-release, 2 months after release, 5 months after release, 8 months after release)

Study Sites (3)

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