JPRN-jRCTs041190124已完成1 期
Involvement of adenosine receptors with inhalation anesthetics: a randomized controlled trial
Sakurai Satoru0 个研究点目标入组 11 人开始时间: 2020年3月6日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 11
研究概览
简要总结
Adenosine receptor stimulation was suggested to cause side effects such as chest discomfort and headache. The combined administration of ATP formulation during general anesthesia with sevoflurane does not cause serious complications and is highly safe. However, the result of this study suggest that the anesthetic (hypnotic) action of sevoflurane was antagonized by adenosine receptors. Since the mechanism is unknown, it is necessary to study further in the future to elucidate it.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 39age old（—）
- 性别
- Male
入选标准
- •1. Healthy adult men aged 20 to 39
- •2. Consent for study participation was obtained by signing consent form for this study
排除标准
- •1. Person who may cause airway obstruction (e.g.: obesity, sleep apnea syndrome)
- •2. Person who have previously used a halogenated anesthetic and have jaundice or an unexplained fever
- •3. Person with a history of hypersensitivity to sevoflurane
- •4. Person taking psychotropic drugs (including taking sleeping pills)
- •5. Person with serious liver disorder, kidney disorder, respiratory disease, heart disease
- •6. Person who is judged unqualified by the study responsible dentist or the study dentist
研究者
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