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Dysfunction of bone marrow progenitor cells in chronic kidney disease

Completed
Conditions
chronic kidney disease
chronic renal failure
10038430
Registration Number
NL-OMON41569
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
38
Inclusion Criteria

CKD patients/kidney recipients:

• CKD patients undergoing renal transplantation procedure
• Age>18 yrs
• Written informed consent.;Donors/healthy controls:

• Healthy controls undergoing renal transplantation donor procedure or voluntarily donate BM during surgery
• Age > 18 yrs
• Written informed consent.

Exclusion Criteria

CKD patients/kidney recipients:

1. Patients undergone stem cell transplantation in the past
2. Based on the exclusion for renal transplantation for CKD:
• Active infection (hepatitis B and C, tuberculosis, HIV);
• Life expectancy <2 years;
• Malignancy not curatively treated;;Donors/healthy controls:

• Kidney disease.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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