Efficacy and safety study ofglycyrrhetinic acid / CMC-Na ointment for oral lichen planus

Phase 1

Recruiting

• Conditions: Oral lichen planus; Lichenoid Eruptions, glycyrrhetinic acid; Lichen Planus, Oral

• Registration Number: JPRN-jRCTs031220306
• Lead Sponsor: chida Fumihiko

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-08-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1) Patients with first-episode oral lichen planus whose pathological diagnosis of oral lichen planus was confirmed by biopsy
2) Steroid-naive patients with oral lichen planus
3) Patients with complaints of pain due to oral lichen planus (Numerical Rating Scale; NRS 1 or more)
4) Patients who are at least 18 years of age at the time of consent
5) Patients who have been fully informed, understand, and give written consent to participate in this study
6) Outpatients

Exclusion Criteria

1) Patients with severe pain due to oral lichen planus (mean NRS 7 or more)
2)Patients with hypersensitivity to the study drug
3) Pregnant patients
4) Patients with active malignancy
5) Patients who are using or will use biologic agents during the study period
6) Patients who are using or will use immunosuppressive drugs during this study
7) Patients receiving steroid therapy for diseases other than lichen planus of the oral cavity
8) Patients with suspected acute abdomen
9) Patients with severe hard stools

Study & Design

• Study Type: Interventional
• Study Design: Not specified