Comparative study of intrathecal Nalbuphine and intrathecal Fentanyl as adjuvant to 0.5% hyperbaric Bupivacaine in abdominal and lower limb surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study duration of postoperative analgesia ,haemodynamics and side effects of Nalbuphine and Fentanyl
研究概览
简要总结
Spinal anaesthesia is the most popular regional anaesthesia technique.Pain is one of the primary concerns after surgery .Many drugs have been used intrathecally as an adjuvant to local anaesthetics to prolong post operative pain relief .Use of intrathecal opioids as adjuncts has a definite place in the present regional anaesthesia practice.Intrathecal opioids are synergistic with local anaesthetics and prolong the duration of postoperative analgesia.Drugs like Morphine,Fentanyl have been used but they have their own side effects. Nalbuphine is an opioid agonist-antagonist recently introduced. It has lesser side effetcs compared to others .There are very few studies comparing N albuphine and Fentanyl .Hence an attempt is being made to comnpare the efficacy of Nalbuphine and Fentanyl in postoperative analgesia and haemodynamics
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA grade 1 and 2 patients Age group of 18-60 years patient willing to give consent patient undergoing abdominal and lower limb surgeries.
排除标准
- •patient allergic to any anaesthetic drug bleeding disorders ASA grade 3 and 4 patient.
- •not willing for consent.
结局指标
主要结局
To study duration of postoperative analgesia ,haemodynamics and side effects of Nalbuphine and Fentanyl
时间窗: 24 hours
次要结局
未报告次要终点
