跳至主要内容
临床试验/CTRI/2020/04/024823
CTRI/2020/04/024823尚未招募不适用

Comparative study of intrathecal Nalbuphine and intrathecal Fentanyl as adjuvant to 0.5% hyperbaric Bupivacaine in abdominal and lower limb surgeries

DRPSIMS RF1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年5月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To study duration of postoperative analgesia ,haemodynamics and side effects of Nalbuphine and Fentanyl

研究概览

简要总结

Spinal anaesthesia is the most popular regional anaesthesia technique.Pain is one of the primary concerns after surgery .Many drugs have been used intrathecally as an adjuvant to local anaesthetics to prolong post operative pain relief .Use of intrathecal opioids as adjuncts has a definite place in the present regional anaesthesia practice.Intrathecal opioids are synergistic with local anaesthetics and prolong the duration of postoperative analgesia.Drugs like Morphine,Fentanyl have been used but they have their own side effects. Nalbuphine is an opioid agonist-antagonist recently introduced. It has lesser side effetcs compared to others .There are very few studies comparing N albuphine and Fentanyl .Hence an attempt is being made to comnpare the efficacy of Nalbuphine and Fentanyl in postoperative analgesia and haemodynamics

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ASA grade 1 and 2 patients Age group of 18-60 years patient willing to give consent patient undergoing abdominal and lower limb surgeries.

排除标准

  • patient allergic to any anaesthetic drug bleeding disorders ASA grade 3 and 4 patient.
  • not willing for consent.

结局指标

主要结局

To study duration of postoperative analgesia ,haemodynamics and side effects of Nalbuphine and Fentanyl

时间窗: 24 hours

次要结局

未报告次要终点

研究者

发起方
DRPSIMS RF
申办方类型
Research institution and hospital

研究点 (1)

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