Effect of flatulent carbohydrates restricted diet on gut microbium and inflammation in patients with ulcerative colitis
- Conditions
- Inflammatory Bowel Disease (Ulcerative Colitis).Ulcerative colitis
- Registration Number
- IRCT20181126041763N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 32
Age over than 20 and under 60 years
Moderate ulcerative colitis (ulcerative colitis diagnosis will be done by a gastroenterologist, using the Mayo score) who are on stable drug therapy. The scores of 6-8 will be considered as moderate UC.
BMI 18.5 to 30 kg/m2
Changed in the type or dosage of their drugs over the past month
Suffered from other gastrointestinal diseases including cancers and infectious diseases
Pregnant or breastfeeding women or those with a decision for pregnancy in the near future
Use of antibiotics
Consumed pre- or pro-biotic products during the last two months
Use tobacco or smoke
Hospitalized in the last three months
Infection over the past 3 months
Suffering from any inflammation-promoting condition
Used multi-vitamin and mineral supplements during the past month
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gut microbiota. Timepoint: Before Intervention and 4 weeks later. Method of measurement: PCR Method.
- Secondary Outcome Measures
Name Time Method Inflammation. Timepoint: Before intervention and 4 weeks later. Method of measurement: ELISA kit.