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Clinical Trials/NCT04602832
NCT04602832
Unknown
Not Applicable

A Randomized Controlled Trial of an Online Well-Being Intervention (The ENHANCE Program) for Improving Individuals Health and Well-Being During the COVID-19 Pandemic

University of British Columbia1 site in 1 country350 target enrollmentOctober 14, 2020
ConditionsWell-Being

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Well-Being
Sponsor
University of British Columbia
Enrollment
350
Locations
1
Primary Endpoint
Perceived Stress Scale (PSS)
Last Updated
5 years ago

Overview

Brief Summary

This study is a randomized controlled trial of an online, evidenced-based intervention (the ENHANCE program) that was modified to address the health and well-being challenges of COVID-19. Eligible participants will be randomized into the ENHANCE or Wait-List Control group over a 12-week period. ENHANCE participants will be introduced, and asked to practice, 10 evidenced-based principles and skills of happiness and well-being. Participants will complete an online survey about their health and well-being at baseline, midway (or 6 weeks), post-assessment (or at the end of the 12-week study), and 3-months following the end of the study.

Detailed Description

The study is designed as a 12-week, two-armed, randomized controlled trail to assess the efficacy of a COVID-19-modified version of the Enduring Happiness and Continued Self-Enhancement (ENHANCE) program. The ENHANCE program represents a 12-week multi-construct, evidenced-based intervention for improving overall happiness and subjective well-being. The ENHANCE program was modified specifically to address the known health and well-being challenges of the COVID-19 pandemic. Eligible participants will be randomized into either the ENHANCE program or Wait-List Control (WLC) group. ENHANCE participants will be introduced to 10 evidenced-based principles that have been shown to improve health and well-being outcomes. Participants will be further guided to systematically practice these principles in their daily lives using a small-changes approach. WLC participants will be asked to continue life a usual, and provided some additional health and well-being resources that can be accessed online to support current, ongoing distress, if needed. Participants will be asked to complete an online survey about their emotional, social, and physical well-being at baseline (or at the start of the study), midway (or 6-weeks into the study), and at post-assessment (or at the end of the study period). At the end of the study period, all control participants will also be offered the full ENHANCE program. Investigators expect that participants receiving the ENHANCE program will show improvements across all negative (e.g., depression, anxiety) and positive (e.g., life satisfaction, quality of life) variables from baseline to post-study. Investigators further expect there to be immediate positive health and economic outcomes linked to active participation in the ENHANCE program (versus the WLC group). Investigators believe the impacts of this research will include (a) mitigating the risk of a severe onset of mental health problems related to anxiety, depression, post-traumatic stress, and suicide, (b) increasing positive mental health and well-being, and (c) increasing physical health in participants across time.

Registry
clinicaltrials.gov
Start Date
October 14, 2020
End Date
December 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Lesley Lutes

Dr. Lesley Lutes, R.Psych.

University of British Columbia

Eligibility Criteria

Inclusion Criteria

  • Individuals who are fluent in English and are 19 years or older.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Perceived Stress Scale (PSS)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline stress

Generalized Anxiety Disorder - 7 (GAD-7)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline anxiety

Beck Depression Inventory - II (BDI-II)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline mood

Patient Health Questionnaire (PHQ-9)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline mood

Positive and Negative Affect Scale (PANAS)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline affect

Health Anxiety Inventory Short-Form (HAI-SF)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline anxiety

Satisfaction With Life Scale (SWLS)

Time Frame: Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months)

Change from baseline satisfaction with life

Secondary Outcomes

  • Sleep Disorder Questionnaire (SDQ)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • PTSD Checklist for the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (PCL-5)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • Meaning In Life Questionnaire (MLQ)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • Paffenbarger Physical Activity Questionnaire (PPAQ)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • University of California, Los Angeles Loneliness Scale (UCLA Loneliness Scale)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • European Quality of Life Group - 5 Dimensions - 5 Levels (EQ-5D-5L)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • World Health Organization Quality of Life (WHOQOL - BREF)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • Measure of Attachment Qualities (MAQ)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))
  • Insomnia Severity Index (ISI)(Baseline, Mid-assessment (6 weeks), Post-assessment (3 months), Follow-up-assessment (6 months))

Study Sites (1)

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