Inflammatory responses of peri-implant crevicular fluid on different dental implant abutment materials after 6-months functional loading: A randomized clinical controlled trial

Completed

• Conditions: Age 18 - 60 years old.Healthy or with well-controlled systemic diseases.Patients who have been treated with single tooth implant in esthetic zone either with or without bone graft on anterior teeth including upper or lower canines, lateral incisors and central incisors at crestal bone level.Screw retained or screw-cement retained implants.Sufficient keratinized gingiva of width of at least 4 mm.Undergone oral prophylaxis treatment and instructions after implant placement.; implant abutment materials; titanium; titanium base; inflammatory responses; peri-implant crevicular fluid; functional loading; randomized clinical controlled trial

• Registration Number: TCTR20240501003
• Lead Sponsor: Faculty of Dentistry, Chulalongkorn University

Brief Summary

Within the limitations of the present study, titanium base abutments presented no significant differences in terms of inflammatory responses compared to titanium abutments after 6 months functional loading. Thus, when used to support single crowns, titanium base can be a feasible treatment alternative to titanium abutments.

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-12-15
• Study Start: 2024-05-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

1. healthy or with well-controlled systemic diseases, 2. patients who have been treated with single tooth implant in esthetic zone (Neodent-Straumann or Straumann, Switzerland) either with or without bone graft on anterior teeth including upper or lower canines, lateral incisors and central incisors at crestal bone level, 3. screw retained or screw-cement retained implants, 4. sufficient keratinized gingiva of width of at least 4 mm, and 5. undergone oral prophylaxis treatment and instructions after implant placement.

Exclusion Criteria

1. medical or general contraindication to the surgical procedure (American Society of Anesthesiologists (ASA) status III), 2. smokers (at least 10 cigarettes per day), 3. poor plaque control or having untreated active periodontal disease, 4. having acute infection including severe swelling of the gingiva, suppuration, and abscess, and 5. being pregnant.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentrations of inflammatory markers before and after 6 months of functional loading Enzyme-linked immunosorbent assays (ELISAs),Clinical responses before and after 6 months functional loading Assessment of probing pocket depth, plaque control, bleeding on probing, and suppuration. ,Radiographic responses before and after 6 months functional loading Periapical radiograh

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A