Effect of kettogenic diet on weight management and apptite

Not Applicable

Recruiting

Conditions: E66.0
Obesity.
Obesity due to excess calories

Registration Number: IRCT20220418054574N1

Lead Sponsor: Vice chancellor for research, Shahid Beheshti University of Medical sciences- School of Nutrition

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

Overweight or obese people between 18-60 years old
Body mass index 40-26 kg / m2
Food addiction based on YFAS4 questionnaire
Weight regain One-third to two-thirds of the weight lost in 1 year, or almost all of them in 5 years
Do not be pregnant or breastfeeding

Exclusion Criteria

gout and chronic diseases such as diabetes, cardiovascular, liver, etc.
mental illness (depression, bipolar disorder and obsessive-compulsive disorder)
Failure to follow a specific diet
take drugs that affect appetite and weight
use any probiotic products in a recent month
use antibiotics during the last month

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Weight. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: seca scale.;Body Mass Index. Timepoint: before intervention, 4 weeks and 8 weeks after intervention. Method of measurement: Calculation (kg/m2).;Waist circumference. Timepoint: before intervention, 4 weeks and 8 weeks after intervention. Method of measurement: Meter strip.;Fat Mass. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Bio Impedance Analyzer.;Fat Free Mass. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Bio Impedance Analyzer.

Secondary Outcome Measures

Name	Time	Method
Serum serotonin level. Timepoint: before intervention, 8 weeks after intervention. Method of measurement: Elisa.;Serum BDNF. Timepoint: before intervention, 8 weeks after intervention. Method of measurement: Elisa.;Gut microbiota. Timepoint: before intervention, 8 weeks after intervention. Method of measurement: PCR.