A randomized controlled trial comparing autologous platelet rich plasma versus only standard treatment for treating burn wounds

Phase 4

Completed

• Conditions: burns; full thickness; 10014982

• Registration Number: NL-OMON35701
• Lead Sponsor: Rode Kruis Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 52

Inclusion Criteria

1. Adult men and women aged 18 years and older (no upper age limit)
2. A full thickness burn which needs primary or secondary transplantation
3. provision of informed consent by patient

Exclusion Criteria

1.Likely problems, in the judgement of the investigators, with maintaining follow-up (e.g.patients with no fixed adress will be excluded)
2. Insufficient comprehension of the Dutch language to understand a rehabilitation program and other treatment information in the judgement of the attending physician.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint is the effect of PRP on the time in days to complete<br /><br>healing of the grafted butn wound sites.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Infection rate of the transplanted burn wounds in comparison with standard<br /><br>treatment.<br /><br>2. Pain meassured daily with a VAS scale to complete healing of the paired<br /><br>grafted burn wound sites.<br /><br>3. Scar assessment with the POSAS scale in comparsion with standard treatment<br /><br>after 3, 6 months and one year. </p><br>