跳至主要内容
临床试验/NCT04435860
NCT04435860已完成不适用

Evaluation of Relationship Between Trunk, Proximal Girdle Muscles' Strength, and Functionality and Disease Activity in Male Patients With Ankylosing Spondylitis

Bezmialem Vakif University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年6月18日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
Cervical muscle powers

研究概览

简要总结

This study evaluates how the trunk and proximal girdle muscles are affected in male patients with ankylosing spondylitis, compared to healthy controls.

详细描述

Ankylosing spondylitis is a chronic, inflammatory rheumatic disease with an unclear etiology which causes back pain and affects the functionality of axial skeleton. Besides the effect upon axial skeleton, the disease also affects the peripheral joints. In most patients, tenuous affection of peripheral joints occurs however, in some others the disease causes impaired spinal mobility and articular instability. This causes proximal girdle muscles and trunk muscles of the patients to be exposed to excessively stress and in conclusion deformities develop. Maximum force generated by a muscle or muscle group directly effects the physical ability of an individual, and manual muscle dynamometers are used to directly evaluate the muscle strength. In this manner the investigators aim to evaluate trunk and proximal girdle muscles' powers in male patients with ankylosing spondylitis and analyze the correlation between muscle powers, and functionality and disease activity.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Having a diagnosis of ankylosing spondylitis according to Modified NewYork criteria

排除标准

  • Severe cardiac or pulmonary or renal disease
  • Accompanying fibromyalgia
  • Severe psychiatric disorder
  • Other disease limiting spinal, shoulder or hip range of motion
  • Myopathy, neuropathy or radiculopathy that may cause muscle weakness
  • Using high dose steroids
  • Endocrinological disorders

结局指标

主要结局

Cervical muscle powers

时间窗: 1 day

Cervical flexion, extension, and lateral flexion muscle powers in kilograms as assessed with handheld dynamometer.

Shoulder girdle muscle powers

时间窗: 1 day

Shoulder flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.

Truncal muscle powers

时间窗: 1 day

Truncal flexion and extension muscle powers in kilograms as assessed with handheld dynamometer.

Hip girdle muscle powers

时间窗: 1 day

Hip flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验