Evaluation of Relationship Between Trunk, Proximal Girdle Muscles' Strength, and Functionality and Disease Activity in Male Patients With Ankylosing Spondylitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Cervical muscle powers
研究概览
简要总结
This study evaluates how the trunk and proximal girdle muscles are affected in male patients with ankylosing spondylitis, compared to healthy controls.
详细描述
Ankylosing spondylitis is a chronic, inflammatory rheumatic disease with an unclear etiology which causes back pain and affects the functionality of axial skeleton. Besides the effect upon axial skeleton, the disease also affects the peripheral joints. In most patients, tenuous affection of peripheral joints occurs however, in some others the disease causes impaired spinal mobility and articular instability. This causes proximal girdle muscles and trunk muscles of the patients to be exposed to excessively stress and in conclusion deformities develop. Maximum force generated by a muscle or muscle group directly effects the physical ability of an individual, and manual muscle dynamometers are used to directly evaluate the muscle strength. In this manner the investigators aim to evaluate trunk and proximal girdle muscles' powers in male patients with ankylosing spondylitis and analyze the correlation between muscle powers, and functionality and disease activity.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Having a diagnosis of ankylosing spondylitis according to Modified NewYork criteria
排除标准
- •Severe cardiac or pulmonary or renal disease
- •Accompanying fibromyalgia
- •Severe psychiatric disorder
- •Other disease limiting spinal, shoulder or hip range of motion
- •Myopathy, neuropathy or radiculopathy that may cause muscle weakness
- •Using high dose steroids
- •Endocrinological disorders
结局指标
主要结局
Cervical muscle powers
时间窗: 1 day
Cervical flexion, extension, and lateral flexion muscle powers in kilograms as assessed with handheld dynamometer.
Shoulder girdle muscle powers
时间窗: 1 day
Shoulder flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.
Truncal muscle powers
时间窗: 1 day
Truncal flexion and extension muscle powers in kilograms as assessed with handheld dynamometer.
Hip girdle muscle powers
时间窗: 1 day
Hip flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.
次要结局
未报告次要终点
