The effectiveness of Pivotal Response Treatment in children and adolescents with autism spectrum disorder: a randomized clinical trail

Phase 2

Completed

• Conditions: ASD; autism; autism spectrum disorder; 10037176

• Registration Number: NL-OMON44124
• Lead Sponsor: Karakter Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 42

Inclusion Criteria

• aged 9 - 15 years at inclusion in the study
• Total Intelligence Quotient (TIQ) of >= 80
• clinically diagnosed with autism spectrum disorder (DSM-IV-TR and DSM-5) or social communication disorder (DSM-5)
• at least one of the parents is able to understand and speak the Dutch language

Exclusion Criteria

-Systemic problems that limit the possibility to engage in an intensive treatment, focused on training both the child/adolescent and parents.
-Presence of comorbid problems that require treatment first.
-Problems with accepting child's diagnosis of ASD by child and/or parent
-Severe parental psychopathology

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Significant response on the SRS (continuous measure): generalized<br /><br>improvement in child's social and communicative skills</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Clinically significant increase at the CGI-I<br /><br>-Generalized social and communicative skills (SRS), percentage of clinical<br /><br>response<br /><br>-Child rearing pressur of parents (OBVL)<br /><br>-Parent-child interaction (PCI)<br /><br>-Change in ASD symptoms (ADOS-2)<br /><br>-Child adaptive behaviour (VABS)<br /><br>-Child internalizing and externalizing symptoms (CBCL)</p><br>