跳至主要内容
临床试验/NCT06278220
NCT06278220尚未招募不适用

Scheimpflug Versus Placido-disc System in Evaluation of Corneal Higher-Order Aberrations Before and After LASIK

Assiut University1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2024年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
36
试验地点
1
主要终点
Agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (pentacam)

研究概览

简要总结

Aim of work:

To assess the agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (Oculus Pentacam ) regard measuring corneal higher order aberrations before and after LASIK.

详细描述

Higher-order aberrations (HOAs) are small optical irregularities of the eye, which can have an impact on the quality of the retinal image. In contrast to lower order aberrations, these errors cannot be corrected with regular spectacles and most contact lenses. Additionally, HOAs are responsible for an array of visual symptoms including dysphotopsia, glare, as well as a reduction in contrast sensitivity. The cornea accounts for approximately 90% of ocular aberrations.Advances and breakthroughs in wavefront aberration measurement technology can help clinicians to better understand and manage corneal higher-order aberrations (HOAs), especially for the preoperative planning of corneal refractive surgery and cataract surgery.A recent study has shown that corneal HOAs can be a sensitive parameter to differentiate early keratoconus from normal eyes. Furthermore, corneal aberrations have been widely used to evaluate dry eye and orthokeratology.LASIK surgery is widely used in the correction of refractive errors It is well known that LASIK surgery induces high-order aberrations (HOA) .The main eye element involved in the generation of such aberrations is the first corneal surface. Currently, devices based on Placido-disc, Hartmann- Shack, ray tracing, or Scheimpflug are routinely used in clinical aberration measurement. Of which Pentacam is one of common instruments that can only measure corneal aberration (including anterior and posterior corneal surface) based on Scheimpflug technology. Also Allegro Topolyzer is a Placido-based topographer that can measure anterior corneal higher order aberrations (HOAs). A better understanding of the agreement of device measurements can provide clinicians with useful information for measuring, correcting, and monitoring aberrations around refractive and cataract surgery. Investigators , therefore, aimed to study the agreement between the two instruments in anterior corneal aberration measurement.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with refractive errors from +6 diopters to -8 diopters sphere and up to -6diopters cylinder.

排除标准

  • Patients with systemic diseases such as diabetes.
  • keratoconus or keratoconus suspect, amblyopic eyes.
  • Patients with best corrected visual acuity (BCVA) not achieving 20/
  • Previous ocular surgeries or trauma.

结局指标

主要结局

Agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (pentacam)

时间窗: Before LASIK and 3 months after LASIK

Agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (pentacam) regard measuring corneal high order aberrations before and after LASIK.

次要结局

  • Changes in high order aberrations after LASIK.(Before LASIK and 3 months after LASIK)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Naglaa Mostafa Abdelhafez Abdelmohsen

Assistant lecturer

Assiut University

研究点 (1)

Loading locations...

相似试验

Scheimpflug Versus Placido-disc System in Evaluation... | 临床试验