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Wearable Movement Sensors for Assessing Motor Impairments and Dyskinesias in Parkinson Disease

Completed
Conditions
Parkinson Disease
Registration Number
NCT01648803
Lead Sponsor
University of Rochester
Brief Summary

The purpose of this study is to measure motor fluctuations and dyskinesias in patients with Parkinson's disease using movement sensors (accelerometers and gyroscopes) to determine if this is a feasible measure to use in addition to self report, and eventually the goal will be to replace self report with a more reliable measure such as movement sensors.

Detailed Description

Patients with Parkinson disease and motor fluctuations will wear movement sensors during their regular clinic visit with the principal investigator. The visit will be videotaped and medication status (ON without dyskinesia, ON with dyskinesia, or OFF) will be independently rated from review of the video.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
12
Inclusion Criteria
  • Participants who will be included in the study have probable or definite idiopathic PD (CAPSIT criteria (23)), Hoehn & Yahr stage 2-4;
  • One or more of the following PD-associated motor impairments experienced in the week prior to enrollment (based on history and/or examination): motor fluctuations (end of dose wearing off with hypokinesia and/or levodopa-induced choreiform dyskinesias), tremor, freezing of gait, or frequent falls (≥ 1 per week).
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Exclusion Criteria
  • Neurological disorders (other than PD) or orthopedic deficits that, in the investigator's judgement, contribute substantially to impaired movement (e.g. stroke with motor sequelae;
  • Essential tremor;
  • Severe osteoarthritis);
  • Cognitive impairment sufficiently severe to interfere with informed consent.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1-3Hz gyroscope signal power30 second windows spanning the observation period
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Rochester

🇺🇸

Rochester, New York, United States

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