Effects of a Variety of Meals on Satiety

Not Applicable

• Conditions: Focus of the Study is Satiety
• Interventions: Other: Acute measures of satiety and food intake at next meal

• Registration Number: NCT01713114
• Lead Sponsor: The Hillshire Brands Company

Brief Summary

The primary objective of this study is to assess the acute effects of different meals on satiety. It is hypothesized that a lower carbohydrate meal will result in greater feelings of satiety and reduced food intake at a subsequent meal compared to the higher-carbohydrate or meal skipping conditions.

Detailed Description

Satiety refers to feelings of fullness or lack of desire to eat following consumption of a food or meal. A number of dietary factors have been shown to influence satiety, including food volume, food weight, energy density, food palatability, and certain food ingredients. The nutritional composition of a meal appears to also play a significant role in an individual's feelings of satiety and ability to stay full until the next meal.

Study Timeline

• Status Verified: 2012-10
• Study Start: 2012-10
• Study First Submitted: 2012-10-22
• Study First Submitted QC: 2012-10-22
• Last Update Submitted: 2012-10-22
• Study First Posted: 2012-10-24
• Last Update Posted: 2012-10-24
• Primary Completion: 2013-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 38

Inclusion Criteria

• premenopausal Females
• Ages 18-55
• BMI between 18.5-29.9
• Willing to maintain weight throughout study period

Exclusion Criteria

• Subject has a history of any surgical intervention for the treatment of obesity
• Recent history or use of weight loss drugs, herbal supplements or on a dieting program or trying to loose weight
• Gains or loses more than 6 pounds over the study period
• Current or history of an eating disorder
• Restrained eater
• Excludes any foods or meals from their diet
• History or presence of clinically important cardiac, renal, hepatic, endocrine, pulmonary, gastrointestinal, biliary, pancreatic or neurologic disorders
• Signs of an infection
• Heavy user of caffeine or alcohol
• Unconventional sleep patterns (e.g. works 3rd shift)
• Subject is pregnant or planning to become pregnant during the study period

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Low carbohydrate	Acute measures of satiety and food intake at next meal	-
Moderate carbohydrate	Acute measures of satiety and food intake at next meal	-
Higher Carbohydrate	Acute measures of satiety and food intake at next meal	-
Meal Skipping	Acute measures of satiety and food intake at next meal	-

Primary Outcome Measures

Name	Time	Method
Composite Area under the Curve - Visual Analog Scale	Acute - up to 4 hrs

Secondary Outcome Measures

Name	Time	Method
Individual satiety measures - Area under the curve	4 hrs

Trial Locations

Locations (1)

Biofortis Clinical Research; 🇺🇸 Addison, Illinois, United States