Impact of corneal collagen cross-linking on vision-related quality of life in patients with progressive keratoconus - QoL in progressive Keratoconus

Augenklinik des Universitätsklinikums Hamburg-Eppendorf (UKE)0 个研究点目标入组 41 人开始时间: 2022年10月4日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•keratoconus (See reference [1]):
•-KISA-index >100 mit I-S >1.4 and/or Kmax>47
•-progressive keratoconus:
•(based on the „Global consensus on keratoconus and extatic diseases[2]): Changes in at least two of the following categories:
•1. progressive steepening of the anterior corneal surface (topography)
•2. progressive steepening of the posterior corneal surface (tomography)
•3. progressive thinning of the corneal thickness
•-> no specific cut-offs due to the recommendation of the „global consensus because different diagnostic devices were used for diagnosing keratoconus (Oculus Pentacam; Ziemer Galilei).
•-> in case of missing corneal diagnostic data to determine a potential progression of the disease, the following alternative criteria are used [3]:
•-decrease of the best corrected visual acuity >= 2 lines (decimal)
•-increase of the refractive astigmatism and/ or the spherical equivalent >= 1 diopter
•[1]: Rabinowitz YS, Rasheed K. KISA% index: a quantitative videokeratography al-gorithm embodying minimal topographic criteria for diagnosing keratoconus. J Cat-aract Refract Surg 1999; 25(10): 1327-35.
•[2]: Gomes JA, Rapuano CJ, Belin MW, et al. Global Consensus on Keratoconus Diagnosis. Cornea 2015; 34(12): e38-9.
•[3]: Hashemi H, Seyedian MA, Miraftab M, et al. Corneal collagen cross-linking with riboflavin and ultraviolet a irradiation for keratoconus: long-term results. Ophthalmo-logy 2013; 120(8): 1515-20.

•-previous ocular surgery
•-previous ocular trauma
•-stopp of contact lens wearing before the measurements <3 days (soft contact lenses) or < 5 days (hard contact lenses)
•-unwillingness to participate in the study/ the necessary follow-up examinations.
•-no written consent form (participation on the study)

发起方

Augenklinik des Universitätsklinikums Hamburg-Eppendorf (UKE)