Biomarkers of Ovarian Reserve and Correlation With IVF Treatments
- Conditions
- Pregnancy, Ovarian
- Registration Number
- NCT02442895
- Lead Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
- Brief Summary
Retrospective study to evaluate the correlation between AFC, FSHb, AMH and IVF outcomes of 347 cycles performed with three different protocols.
- Detailed Description
347 IVF cycles (236 patients) analyzed for a retrospective study to evaluate the correlation between the biomarkers of ovarian reserve (antral follicles count, antimullerian hormone, basal follicle stimulating hormone) and number of oocytes and mature oocytes (MII) retrieved during the pick up. For the stimulation were used three different protocols: long luteal, antagonist with daily administration of gonadotropins and antagonist with depot administration of gonadotropins.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 236
- women with primary or secondary infertility underwent ovarian stimulation for in vitro fertilization.
- women who underwent ovarian stimulation for cryopreservation in the presence of neoplastic disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method number of total and mature (MII) oocytes 10 months the number of total and mature (MII) oocytes retrieved during the pick up.
- Secondary Outcome Measures
Name Time Method duration of stimulation 10 months the number of days since the administration of rFSH o corifollitropina alfa until the administration of hCG
ovarian sensitivity index or OSI 10 months OSI was calculated dividing the total administered FSH dose by the number of retrieved oocytes
pregnancy rate 10 months the number of positive pregnancy tests with the evidence of an embyo with cardiac activity.
Trial Locations
- Locations (1)
Azienda Ospedaliero Universitaria Consorziale Policlinico
🇮🇹Bari, Italy