CTRI/2025/05/086604Not yet recruitingPhase 2/3
Comparison of efficacy of Preoxygenation standard face mask along with apnoeic oxygenation with nasal cannula versus face mask alone in patients undergoing intubation in emergency: A randomized control trial.
no sponser1 site in 1 country618 target enrollmentStarted: May 18, 2025Last updated:
Trial Snapshot
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 618
- Locations
- 1
- Primary Endpoint
- lowest oxygen saturation during the interval between induction of anaesthesia till 2 minutes after tracheal intubation
Study Overview
Brief Summary
The pre oxygenation with standard face mask along with apnoeic oxygenation using nasal cannula can better prevent oxygen desaturation during procedure of intubation as compared to pre oxygenation with face mask alone.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Open Label
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Inclusion criteria includes patient coming to emergency department age more than 18, requiring intubation and willing to take part in trial.
Exclusion Criteria
- •Patient in cardiac arrest
- •Pregnant and breast feeding
- •Already receiving positive pressure ventilation
- •Patient requiring delayed sequence intubation 5.
Outcomes
Primary Outcomes
lowest oxygen saturation during the interval between induction of anaesthesia till 2 minutes after tracheal intubation
Time Frame: the interval between induction of anaesthesia before intubation till 2 minutes after the procedure of intubation is completed.
Secondary Outcomes
- Severe hypoxemia during intubation i.e. oxygen saturation of less than 80%.(Interval from induction of anaesthesia till 2 minutes after tracheal intubation.)
- hypoxemia during intubation i.e. oxygen saturation of less than 90 %.(Interval from induction of anaesthesia till 2 minutes after tracheal intubation)
- hypoxemia post intubation i.e. oxygen saturation of less than 90%.(During the interval from 2 to 15 minutes after tracheal intubation)
- Change in oxygen saturation(Recorded before pre oxygenation & after 3 minutes of pre oxygenation.)
Investigators
Study Sites (1)
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