Comparison of efficacy of Preoxygenation which is done before intubation with face mask along with apnoeic oxygenation with nasal cannula versus face mask alone which is standard method in patients undergoing intubation in emergency: A randomized control trial.

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2025/05/086604
• Lead Sponsor: no sponser

Brief Summary

The pre oxygenation with standard face mask along with apnoeic oxygenation using nasal cannula can better prevent oxygen desaturation during procedure of intubation as compared to pre oxygenation with face mask alone.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-05-18
• Last Update Posted: 2025-07-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 618

Inclusion Criteria

Inclusion criteria includes patient coming to emergency department age more than 18, requiring intubation and willing to take part in trial.

Exclusion Criteria

• Patient in cardiac arrest 2.
• Pregnant and breast feeding 3.
• Already receiving positive pressure ventilation 4.
• Patient requiring delayed sequence intubation 5.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
lowest oxygen saturation during the interval between induction of anaesthesia till 2 minutes after tracheal intubation	the interval between induction of anaesthesia before intubation till 2 minutes after the procedure of intubation is completed.

Secondary Outcome Measures

Name	Time	Method
hypoxemia during intubation i.e. oxygen saturation of less than 90 %.	Interval from induction of anaesthesia till 2 minutes after tracheal intubation
Severe hypoxemia during intubation i.e. oxygen saturation of less than 80%.	Interval from induction of anaesthesia till 2 minutes after tracheal intubation.
hypoxemia post intubation i.e. oxygen saturation of less than 90%.	During the interval from 2 to 15 minutes after tracheal intubation
Change in oxygen saturation	Recorded before pre oxygenation & after 3 minutes of pre oxygenation.

Trial Locations

Locations (1)

AIIMS RISHIKESH; 🇮🇳 Dehradun, UTTARANCHAL, India

AIIMS RISHIKESH

🇮🇳Dehradun, UTTARANCHAL, India

Dr Parampreet singh

Principal investigator

8607944989

parampreetsinghynr@gmail.com