Identification of biomarkers for diagnosis of major depressio
Not Applicable
- Conditions
- Major depressive disorder
- Registration Number
- JPRN-UMIN000025307
- Lead Sponsor
- Shinshu University
- Brief Summary
The salivary levels of IL-1beta, IL-6, IL-9, IL-12p70, IL-13, Chemokine CCL11 (Eotaxin), MIP-1alpha, RANTES, and VEGF were significantly higher in patients than controls. IL-1beta, IL-12p70, CCL11, and VEGF remained significant after controlling for possible confounding factors.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 69
Inclusion Criteria
Not provided
Exclusion Criteria
1. Suffers from any inflammatory, endocrine, or metabolic disorders or suffers from severe periodontal disease. 2. Has taken anti-allergic medication, steroid, or immunosuppressant medication in the past month. 3. Suffers from organic brain disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hamilton depression rating scale, Montgomery-Asberg Depression Rating Scale, and salivary levels of cortisol, alpha-amylase, and cytokines.
- Secondary Outcome Measures
Name Time Method