Efficacy of the fibrinogen and Fresh frozen plasma in patients with severe trauma
Phase 1
- Conditions
- Trauma.Other early complications of trauma
- Registration Number
- IRCT2017051923559N13
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Age over 18 years old; patients with multiple trauma; need for repeated transfusion; injury severity score 16 and above; satisfaction to participate in the study. Exclusion criteria: Unwillingness of the patient to continue cooperation in the plan; trauma limited to head; Penetrating trauma; injury severity score less than 16.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: 4 and 12 hours after the beginning of the intervention. Method of measurement: Manual blood pressure monitor.;Blood PH. Timepoint: 4 and 12 hours after the beginning of the intervention. Method of measurement: Lab.;Oxygenation index. Timepoint: 4 and 12 hours after the beginning of the intervention. Method of measurement: Lab.
- Secondary Outcome Measures
Name Time Method Types of brain and organ damage. Timepoint: At the beginning of the intervention. Method of measurement: Imaging through CT scan.;Level of consciousness. Timepoint: At the beginning of the intervention. Method of measurement: Using the Glasgow Coma Score.;Days requiring mechanical ventilation. Timepoint: During hospital admission. Method of measurement: Counting the days required for mechanical ventilation.;Number of blood units taken. Timepoint: During the days of admission. Method of measurement: Count of injected blood units.;Duration of hospitalization. Timepoint: Time of discharge. Method of measurement: Count the number of admitted days.;Patients death. Timepoint: End of intervention. Method of measurement: Clinical.