Intervention Targeting Substance Using Older Adults With HIV
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Adherence to HIV medication
研究概览
简要总结
The proposed study uses a randomized controlled experimental design to evaluate the efficacy of a brief intervention using spiritual self schema (3S+) counseling to simultaneously target HIV health outcomes, and substance use among alcohol and/or drug dependent HIV positive older adults (age 50+), relative to an attention control condition. Participants will be randomly assigned to receive either: (1) 12 sessions of 3S+ counseling, adapted for the present study to target both non-injection drug use, drinking, and HIV health; or (2) 12 sessions of education about HIV health and the associated with alcohol and drug use that will serve as an attention-control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV+ (provide HIV medication bottle with name on it)
- •Age 50 or older (provide picture ID with DOB at baseline)
- •Report current alcohol/drug dependence (AUDIT score of 8 or DAST-10 score of 4 on screener; C-DIS at baseline)
- •On a prescribed HAART medication regimen and reports sub-optimal adherence (self-report missed at least 3 days in last 30 at 1 pill/day that is 90%)
- •Communicate with staff and complete a survey in English or Spanish (English only for the pilot)
排除标准
- •Current intravenous drug use (self-report at screener and baseline)
- •Currently in a methadone drug treatment program (screener self-report)
- •Unstable, serious psychiatric symptoms (SCID-Psych at baseline)
- •Currently suicidal/homicidal (SCID-Psych at baseline)
- •Gross cognitive impairment (Mini-Mental at baseline)
- •Current enrollment in alcohol/drug treatment or HIV study (screener self-report)
结局指标
主要结局
Adherence to HIV medication
时间窗: every four months over the course of a year
Participants in the intervention condition will report greater reductions in viral load, and greater increases in CD4 counts and self-reported adherence than those in the education comparison at the end of the intervention period (4 months). Those in the intervention condition will also maintain greater reductions in viral load, and greater increases in CD4 counts and self-reported adherence than those in the education comparison condition at the three follow-up assessments (4, 8, and 12 months).
Substance use
时间窗: every four months over the course of a year
Participants in the intervention condition will report greater reductions in self-reported days of substance use and severity of dependence than those in the education comparison at at the end of the intervention period (4 months). Those in the intervention condition will also maintain greater reductions in self-reported days of substance use than those in the education comparison condition at the three follow-up assessments (4, 8, and 12 months).
次要结局
- Mental Health/Quality of Life(every four months over the course of a year)
- Sexual Risk(every four months over the course of a year)
研究者
Jeffrey T. Parsons
Professor
Hunter College of City University of New York