Treatment of functional symptoms due to work-related stress

Completed

• Conditions: Stress, adjustment disorders; Mental and Behavioural Disorders; Reaction to severe stress, and adjustment disorders

• Registration Number: ISRCTN52839015
• Lead Sponsor: Trygfonden (Denmark)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04-15
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 210

Inclusion Criteria

1. Adults aged 18 - 64 years, either sex
2. Employed
3. On sick leave
4. Moderate to high stress symptom score

Exclusion Criteria

1. If alcohol or substance abuse has contributed substantially to the load condition
2. Unemployment
3. Major illnesses for example cancer and heart diseases, which has contributed substantially to the load condition
4. Physically impaired abilities, which prevent physical activity as a fast walk
5. Major mental disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Return to work rate, measured at 4 months and one year.

Secondary Outcome Measures

Name	Time	Method
1. Symptom Checklist 92, measured at 4 months<br>2. World Health Organization (WHO) Major Depression Inventory, measured at 4 months<br>3. Absenteeism, measured at 4 months<br>4. Copenhagen Psychosocial Questionnaire (COPSOQ), measured at 4 months<br>5. Objective measures: <br>5.1. Salivary cortisol, measured at 4 months <br>5.2. High density lipoprotein (HDL) cholesterol, total cholesterol, blood pressure, measured at 4 months<br>5.3. C-reactive protein (CRP) and interleukin-6 (IL-6) (immunological status), measured at 4 months<br>5.4. HbA1C and dehydroepiandrosterone sulfate (DHEA-S) (metabolic condition), measured at 4 months<br>5.5. Heart rate variability (HRV), measured at 4 months<br>5.6. Neo Pi-r Personality Inventory (personality testing), measured at baseline