The Effect of β-hydroxy-β-methylbutyrate (HMB) Supplementation on Physical Capacity and Body Composition in Trained Athletes
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 58
- 试验地点
- 2
- 主要终点
- Changes of aerobic capacity after HMB supplementation
研究概览
简要总结
The purpose of this study was to verify the effect of 12-week with β-hydroxy-β-methylbutyrate (HMB) and a placebo (PLA) supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
详细描述
The effect of HMB supplementation is of great interest in sport. In view of the inconclusive character of the results of the studies conducted to date and of a relatively low number of studies investigating the effectiveness of HMB supplementation over a longer period on a large population of trained athletes, the aim of this study was to verify the effect of 12-week with HMB and a placebo supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 40 Years（Child, Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •written consent to participate,
- •a current medical clearance to practice sports,
- •training experience: at least 5 years,
- •minimum of 6 workout sessions a week (minimum 3 in the practiced sports discipline).
排除标准
- •current injury,
- •any health-related contraindication,
- •declared general feeling of being unwell,
- •unwilling to follow the study protocol.
结局指标
主要结局
Changes of aerobic capacity after HMB supplementation
时间窗: Baseline and after 12 weeks
Changes of body composition indices after HMB supplementation
时间窗: Baseline and after 12 weeks
Analysis of the fat mass and fat free mass
Changes of aerobic capacity after placebo treatment
时间窗: Baseline and after 12 weeks
Changes of creatine kinase and lactate dehydrogenase activity in blood after HMB supplementation
时间窗: Baseline and after 12 weeks
Changes of testosterone, cortisol and lactate levels in blood after HMB supplementation
时间窗: Baseline and after 12 weeks
Changes of anaerobic capacity after placebo treatment
时间窗: Baseline and after 12 weeks
Changes of testosterone, cortisol and lactate levels in blood after placebo treatment
时间窗: Baseline and after 12 weeks
Changes of body composition indices after placebo treatment
时间窗: Baseline and after 12 weeks
Analysis of the fat mass and fat free mass
Changes of creatine kinase and lactate dehydrogenase activity in blood after placebo treatment
时间窗: Baseline and after 12 weeks
Changes of anaerobic capacity after HMB supplementation
时间窗: Baseline and after 12 weeks
次要结局
- Statistical evaluation of the significance of differences between the changes in body composition (fat mass and fat free mass)(1 year)
- Statistical evaluation of the significance of differences between the changes in creatine kinase and lactate dehydrogenase activity and testosterone, cortisol and lactate levels in blood(1 year)
- Statistical evaluation of the significance of differences between the changes in aerobic capacity indices(1 year)
- Statistical evaluation of the significance of differences between the changes in anaerobic capacity indices(1 year)
研究者
Krzysztof Durkalec-Michalski
Assistant Professor
Poznan University of Medical Sciences