Functional Outcomes and HRQoL in Upper-extremity Sarcoma Patients After Limb Salvage

Completed

• Conditions: Cancer of Muscle

• Registration Number: NCT02380651
• Lead Sponsor: Helsinki University Central Hospital

Brief Summary

This study aims to assess the functional ability and health-related quality of life (HRQoL) of upper extremity sarcoma patients who have undergone limb salvage surgery.

Detailed Description

The purpose of this study is to assess the functional capabilities and health-related quality of life (HRQoL) of upper-extremity sarcoma patients who have undergone limb salvage surgery.

Patient hospital records are retrospectively reviewed for demographic and clinical data.

The patient recruitment takes place at the outpatient clinic of the Comprehensive Cancer Center, Helsinki University Hospital, and Tampere University Hospital. The study includes a cross-sectional assessment at six months follow-up with five validated questionnaires. A follow-up is conducted two and five years after surgery in the outpatient clinic.

Study Timeline

• Study First Submitted: 2015-03-01
• Study First Submitted QC: 2015-03-01
• Study First Posted: 2015-03-05
• Study Start: 2015-12
• Primary Completion: 2018-09
• Study Completion: 2018-09
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-15
• Last Update Posted: 2021-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

• Upper extremity soft tissue sarcoma locating in between scapula to arm
• No metastasis at the time of diagnosis
• Undergone limb salvage surgery
• A minimum of 6 months follow-up
• Written consent
• Age > 18

Exclusion Criteria

• Age <18
• No limb-salvage surgery due to sarcoma
• Deceased

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Health-related quality of life and upper-extremity functional capability	6 months to five years	To assess health-related quality of life and upper-extremity functional capability

Secondary Outcome Measures

Name	Time	Method
The MSTS upper extremity section	6 months to five years	to assess the upper-extremity function
the 15D health-related quality of life instrument	6 months to five years	to assess the health-related quality of life
The QuickDASH	6 months to five years	to assess the upper-extremity function
Sarcoma recurrence	6 months to five years	to assess sarcoma recurrence
Quality of Life Questionnaire-Core 30	6 months to five years	to assess the health-related quality of life
The TESS upper extremity section	6 months to five years	to assess the upper-extremity function

Trial Locations

Locations (2)

Tampere University Hospital; 🇫🇮 Tampere, Finland

Helsinki University Central Hospital; 🇫🇮 Helsinki, Uusimaa, Finland