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临床试验/CTRI/2025/12/098759
CTRI/2025/12/098759尚未招募3 期

A comparative study between continuous adductor canal block versus epidural analgesia for postoperative pain management in total knee arthroplasty patients

Guru Gobind Singh Medical College Hospital1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年3月1日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
80
试验地点
1

研究概览

简要总结

This study compares the postoperative analgesic efficacy of continuous adductor canal block (CACB) and continuous epidural analgesia (CEA) in patients undergoing elective total knee arthroplasty under spinal anaesthesia. A total of 80 ASA I–II patients aged 40–75 years will be allocated into two groups of 40 each. Group A will receive ultrasound-guided CACB with continuous infusion of 0.125% levobupivacaine with fentanyl, while Group B will receive continuous epidural infusion of the same drug combination. Pain intensity will be assessed using the Visual Analogue Scale (VAS) at 6, 12, 24, and 48 hours. Secondary outcomes include need for rescue analgesia, total opioid consumption, range of motion, day of ambulation, patient satisfaction scores, hemodynamic stability, and any complications encountered. The study aims to evaluate whether CACB provides effective pain relief with better preservation of motor function and fewer adverse effects compared to epidural analgesia, thereby supporting improved postoperative recovery after knee arthroplasty.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
40.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • ASA grade I and II patients.

排除标准

  • Subjects with history of allergy to local anaesthetics.
  • Pregnant or lactating females.
  • Infection or scarring at the site of Adductor Canal Block (ACB) /epidural block.
  • Psychological disorders or linguistic difficulties that might interfere with pain assessment.
  • History of bleeding disorders and coagulopathy.

研究者

发起方
Guru Gobind Singh Medical College Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Rahul Ahuja

Guru Gobind Singh Medical College Hospital, Faridkot

研究点 (1)

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