Effects of High-absorptive Curcumin on Oxidative Stress Caused by Smoking
- Conditions
- Smoker
- Registration Number
- JPRN-UMIN000003853
- Lead Sponsor
- ational Hospital Organization Kyoto Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Not provided
1) Unstable angina, recent (< 3 months) myocardial infarction, severe coronary heart disease (left main trunk or 3 vessel disease), and recent (=< 3 months) orplanned (=< 6 months) AC bypass surgery / PCI 2) Severe arrhythmia (sustained ventricular tachycardia, ventricular fibrillation, and severe bradycardia with an indication of pacemaker implantation 3) Moderate or severe valvular diseases 4) Cardiomyopathy or progressive myocarditis 5) Severe respiratory diseases 6) Cardiogenic shock or systolic blood pressure < 80 mmHg 7) Renal failure (Cre >= 4.0 mg/dL or dialysis) 8) Severe liver dysfunction or liver cirrhosis 9) Recent (< 3 months) cerebrovascular disease 10) Malignancy 11) Poorly controlled diabetes (HbA1c >= 8.0%) 12) Anemia (Hb < 6.0 mg/dL) 13) Use of steroid 14) Past history of Curcumin allergy 15) Pregnancy, nursing, or a wish for pregnancy within 6 months 16) etc
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum levels of oxidative stress markers
- Secondary Outcome Measures
Name Time Method Serum levels of possible novel biomarkers of cardiovascular risk
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