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Clinical Trials/KCT0000391
KCT0000391
Completed
未知

Continuous infusion versus intermittent dosing of pantoprazole for the prevention of bleeding after endoscopic submucosal dissection : A prospective randomized trial

Pusan National University Hospital0 sites400 target enrollmentTBD
ConditionsNeoplasms

Overview

Phase
未知
Intervention
Not specified
Conditions
Neoplasms
Sponsor
Pusan National University Hospital
Enrollment
400
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
7 years ago
Study Type
Interventional Study
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • a. gastric adenoma(no limitation in size)
  • b. early gastric cancer /c no LN involvement and metastasis by abdominal CT (expanded criteria by Gotoda et. al)
  • ? differentiated type
  • \- mucosal cancer without ulcer finding irrespective of tumor size
  • \- mucosal caner with ulcer finding \= 3cm
  • \- minute (\<500um from muscularis mucosa) submucosal invasive cancer \= 3cm
  • ? undifferentiated type
  • \- mucosal cancer without ulcer finding \= 2cm

Exclusion Criteria

  • a. previous history of UGI surgery or vagotomy
  • b. known hypersensitivity on pantoprazole
  • c. current use of aspirin, antiplatelet, anticoagulant, NSAIDs, steroid
  • d. current use of PPI
  • e. abnormal coagulation profile
  • f. women either pregnant or at risk of pregnancy
  • g. lactating women
  • h. ASA III or IV or severe comorbidity
  • e. reccured lesion

Outcomes

Primary Outcomes

Not specified

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