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Clinical Trials/NCT02451605
NCT02451605
Unknown
Not Applicable

Regional Blockade for Knee Prothesis Surgery: Comparison Between Femoral, Sciatic and Adductor Canal Block

University of Liege1 site in 1 country40 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Analgesic nerve blockade (Ropivacaine)
Conditions
Total Knee Replacement
Sponsor
University of Liege
Enrollment
40
Locations
1
Primary Endpoint
Pain measurement with numeric pain scale : from 0 to 10 (maximal pain) in rest condition
Last Updated
10 years ago

Overview

Brief Summary

Comparison of the analgesics blocks (femoral, adductor canal and sciatic subgluteal nerve) for total replacement knee surgery.

Detailed Description

Adductor canal block shows a beneficial effect for knee surgery. Mainly because he prevent for muscular weakness; adverse effect meet with femoral block and delaying the early active mobilization. The investigators want to compare the efficacy and safety of this block compared to the femoral and sciatic block.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
December 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Pierre Goffin

Clinical assistant

University of Liege

Eligibility Criteria

Inclusion Criteria

  • patients scheduled for total knee replacement surgery.

Exclusion Criteria

  • refusal to study,
  • coagulation disorder,
  • infection at the puncture site,
  • preexisting neuropathy,
  • allergy to local anesthetics,
  • renal or hepatocellular insufficiency,
  • context of chronic pain,
  • drugs abuse,
  • pregnant patient.

Arms & Interventions

Femoral nerve blockade

In this group, patient will benefit of an ultrasound guided femoral nerve blockade with continuous catheter infusion as (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Intervention: Analgesic nerve blockade (Ropivacaine)

Femoral nerve blockade

In this group, patient will benefit of an ultrasound guided femoral nerve blockade with continuous catheter infusion as (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Intervention: Total knee replacement surgery.

Adductor canal blockade

In this group, patient will benefit of an ultrasound guided adductor canal blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for for total knee replacement surgery.

Intervention: Analgesic nerve blockade (Ropivacaine)

Adductor canal blockade

In this group, patient will benefit of an ultrasound guided adductor canal blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for for total knee replacement surgery.

Intervention: Total knee replacement surgery.

Subgluteal sciatic nerve blockade

In this group, patient will benefit of an ultrasound guided subgluteal sciatic nerve blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Intervention: Analgesic nerve blockade (Ropivacaine)

Subgluteal sciatic nerve blockade

In this group, patient will benefit of an ultrasound guided subgluteal sciatic nerve blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Intervention: Total knee replacement surgery.

Outcomes

Primary Outcomes

Pain measurement with numeric pain scale : from 0 to 10 (maximal pain) in rest condition

Time Frame: up to day 7

Pain assessment and evolution in postoperative period (passive condition)

Pain measurement with numeric pain scale (from 0 to 10) during active motorized mobilization (Kinetic)

Time Frame: up to day 7

Pain assessment and evolution in postoperative period (active condition)

Secondary Outcomes

  • Opioid consumption(up to 48 hours)
  • Patient satisfaction(at day 1)
  • Postintervention nausea vomiting(at hour 0, at hours 6, at day 1)

Study Sites (1)

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