NL-OMON51533招募中不适用
A dynamic, multiple-biomarker approach aiming for individualized treatment of heart failure with preserved ejection fraction - ADAPT-HFpEF
niversitair Medisch Centrum0 个研究点目标入组 200 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Age of 18 years or older
- •- Capable of understanding and signing informed consent
- •- A diagnosis of HFpEF according to the HFA-PEFF diagnostic algorithm of the
- •- a high (90%) probability of HFpEF according to the H2FPEF score, i.e. a score
- •of 6 or higher
排除标准
- •-History of LVEF <=40%
- •-Scheduled for surgery or intervention for both coronary and non-coronary
- •indication within 6 months of inclusion
- •-Impaired renal function, defined as eGFR < 20 mL/min/1.73 m2 (CKD-EPI) or
- •requiring dialysis at the time of screening
- •-Acute or chronic liver disease, defined by serum levels of transaminases or
- •alkaline phosphatase more than three times the upper limit of normal at
- •-COPD Gold stage IV
- •-Congenital heart disease
- •-Pregnancy
- •-Coexistent condition with life expectancy of <1 year
- •-Unlikely to appear at all scheduled follow-up visits
- •-Linguistic barrier
研究者
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