Impact of Symptomatic Hyperventilation on Respiratory Parameters and Functional Capacity Among Individuals Living With Stroke: A Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 92
- 主要终点
- Change in Forced Expiratory Volume in One Second (FEV1 % predicted)
研究概览
简要总结
This study will investigate the effects of hyperventilation syndrome on respiratory muscle strength, respiratory muscle endurance, pulmonary functions, and functional capacity in individuals living with stroke, and in this context, stroke patients with and without hyperventilation syndrome based on Nijmegen Questionnaire scores will be compared to evaluate the relationship between symptom burden and respiratory parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals who will be diagnosed with a confirmed first-ever or recurrent stroke (ischaemic or haemorrhagic) verified by neuroimaging (CT or MRI).
- •Individuals who will be in the chronic or subacute post-stroke period (medically stable following stroke onset).
- •Individuals aged 18 years and older.
- •Individuals who will be classified into either the hyperventilation syndrome group based on a Nijmegen Questionnaire score of ≥23 or the control group based on a score of <
- •Individuals who will be able to comprehend instructions and cooperate adequately with pulmonary function tests, respiratory muscle testing, and physical performance assessments.
- •Individuals who will provide written informed consent to participate in the study.
排除标准
- •Individuals who will present with severe cognitive impairment, aphasia, or psychiatric disorders that will prevent reliable completion of questionnaires (such as the Nijmegen Questionnaire) or cooperation with test procedures.
- •Individuals who will have pre-existing primary chronic obstructive pulmonary disease (COPD), asthma, restrictive thoracic diseases, or other major pre-existing pulmonary pathologies that will confound pulmonary function test results.
- •Individuals who will have unstable cardiovascular conditions (e.g., recent myocardial infarction within the past 3-6 months, unstable angina pectoris, uncontrolled malignant arrhythmias, or uncontrolled severe hypertension) that will pose a risk during physical testing (such as the six-minute walk test).
- •Individuals who will have severe orthopedic, musculoskeletal, or lower extremity peripheral disorders unrelated to stroke that will independently limit functional capacity and walking distance (6MWD).
- •Individuals who will have active respiratory tract infections or acute pulmonary illnesses at the time of evaluation. Individuals who will be participating in an active pulmonary rehabilitation program or receiving respiratory muscle training concurrently.
研究组 & 干预措施
Without Hyperventilation Syndrome Group
干预措施: Respiratory Function, Respiratory Muscle Strength, and Functional Capacity Assessments (Other)
Hyperventilation Syndrome Group
干预措施: Respiratory Function, Respiratory Muscle Strength, and Functional Capacity Assessments (Other)
结局指标
主要结局
Change in Forced Expiratory Volume in One Second (FEV1 % predicted)
时间窗: Measured at baseline/assessment
FEV1 percent predicted values will be measured to evaluate and compare pulmonary function between the hyperventilation syndrome group and the control group.
Maximal inspiratory pressure (PImax)
时间窗: Measured at baseline/assessment.
Maximal inspiratory pressure will be assessed to determine respiratory muscle strength.
次要结局
- Peak Expiratory Flow (PEF)(Measured at baseline/assessment.)
- Maximal expiratory pressure (PEmax)(Measured at baseline/assessment.)
- Respiratory Muscle Endurance Score(Measured at baseline/assessment.)
- Forced Vital Capacity (FVC)(Measured at baseline/assessment.)
- Six-Minute Walk Distance (6MWD)(Measured at baseline/assessment.)
研究者
Yunus Emre Tutuneken
Dr. Assistant Professor
Istinye University