efficacy of simvastatin gel local drug delivery in the management of gum diseases
- Conditions
- Health Condition 1: null- CHRONIC PERIODONTITIS
- Registration Number
- CTRI/2015/06/005910
- Lead Sponsor
- ANU R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
•Systemically healthy patient diagnosed with generalised or localized (more than two sites) chronic periodontitis with bilateral intrabony defects
•Clinical probing pocket depth >= 5 mm in 2 sites .
•Radiographic evidence of bilateral intrabony defects in any 2 region
•History of antibiotics in last 2 months
• History of periodontal therapy in last 6 months
• Suspected allergy to statin group
• Patients on systemic statin therapy
• Aggressive periodontitis
•Tooth with grade 3 mobility
• Current smokers
• Immunocompromised patient
• Pregnant and lactating females
•Blood disorders
•Any other contraindication for periodontal surgery
•Patients indicated for multiple extractions/undergone multiple extractions
•Diabetes
•Any systemic disorders.
•Patients with dental infections like chronic periapical lesions,Apthous stomatitis,Oral lichenplanus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plaque index <br/ ><br>probing pocket depth <br/ ><br>clinical attachment level RecessionTimepoint: Plaque index <br/ ><br>probing pocket depth <br/ ><br>clinical attachment level Recession
- Secondary Outcome Measures
Name Time Method : radiographic evaluation of bone fillTimepoint: : radiographic evaluation of bone fill