Comparing the efficacy of two antibiotic groups for gram negative sepsis in intensive care unit
Phase 1
- Conditions
- Health Condition 1: R99- Ill-defined and unknown cause of mortalityHealth Condition 2: I958- Other hypotensionHealth Condition 3: B998- Other infectious diseaseHealth Condition 4: J17- Pneumonia in diseases classified elsewhereHealth Condition 5: R579- Shock, unspecified
- Registration Number
- CTRI/2024/04/065863
- Lead Sponsor
- Trishita Saha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
patients giving consent and age more than 18 years and culture positive for MBL.
Exclusion Criteria
The patient/relatives who refuse to give informed consent and Age less than 18 years andPatients having gram negative infections caused by CRAB/Non MBL and Pregnant females and Moribund and Brain dead patients and Patients with known allergy to given drug regime.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method primary outcome is To compare the cure rate among two groups by culture negative report. <br/ ><br>Timepoint: 6 months
- Secondary Outcome Measures
Name Time Method The secondary objectives will be <br/ ><br>To observe the Procalcitonin (PCT) and Proadrenomedullin levels in both the groups. <br/ ><br>To compare the neutrophil to lymphocyte ratio(NLR) in both the groups.To determine the length of ICU stay in both groups.To find out the 28-day all-cause mortality in both groups <br/ ><br>Timepoint: 6 months