JPRN-UMIN000014927
Completed
Phase 1
Phase I trial of definitive chemoradiotherapy with paclitaxel, cisplatin, and 5-FU (PCF-RT) for esophageal cancer - Phase I trial of definitive chemoradiotherapy with paclitaxel, cisplatin, and 5-FU (PCF-RT) for esophageal cancer
Aichi Cancer Center Hospital0 sites18 target enrollmentAugust 22, 2014
Conditionsesophageal cancer
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- esophageal cancer
- Sponsor
- Aichi Cancer Center Hospital
- Enrollment
- 18
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Histologically proven squamous cell carcinoma or adenocarcinoma or adenosquamous cell carcinoma or basal cell carcinoma of the esophagus 2\) Primary lesion are located within the thoracic esophagus (Te) 3\) Clinical stage I or II or III or IV (with supraclavicular LN) 4\) Total radiation dose is 50\.4Gy 5\) Aged 20 to 75 years old 6\) ECOG PS of 0 or1 7\) no need for measurable lesion 8\) no previous treatment of esophageal cancer except EMR or ESD 9\) no previous chemotherapy or radiotherapy against any other malignancies 10\) adequate organ functions 11\) refused esophagectomy 12\) written informed consent
Outcomes
Primary Outcomes
Not specified
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