Hypertension, Ethnicity and Exercise Trial

Not Applicable

Completed

• Conditions: Hypertension

• Registration Number: NCT06824805
• Lead Sponsor: KU Leuven

Brief Summary

The main aim of this study is to investigate the acute effects of a single bout of isometric handgrip exercise (IHG) and a single bout of aerobic endurance exercise (AEX) on blood pressure, both immediately after exercise and during the subsequent activities of daily living in patients with high-normal to grade 1 hypertension of South-Asian or African descent living in Suriname.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-01
• Primary Completion: 2023-11-30
• Study Completion: 2023-11-30
• Status Verified: 2025-02
• Study First Submitted: 2025-02-10
• Study First Submitted QC: 2025-02-10
• Last Update Submitted: 2025-02-10
• Study First Posted: 2025-02-13
• Last Update Posted: 2025-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• • Age 18 - 65 years

  • Patients with high- normal BP (SBP: 130 - 139 mmHg or and DBP: 85 - 89 mmHg) or stage I hypertension (SBP: 140 - 159 mmHg or DBP: 90 - 99 mmHg) according to the ESC/ESH guidelines [15]
  • Asian or African descent
  • Do not meet the level of physical activity recommended by the WHO based on self-report [15]
  • Non-medicated patients or patients using a maximum of 2 antihypertensive drugs

Exclusion Criteria

• • Functional or mental limitation limiting the correct execution of an exercise bout

  • History of ischemic stroke, autonomic neuropathy, cardiovascular, renal, or pulmonary disease by self-report
  • Diabetes type I or II
  • Pregnancy
  • The presence of exercise induced signs of myocardial ischemia or complex ventricular arrhythmia during CPET
  • Patients using three or more antihypertensive drugs or patients with resistant hypertension

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
office blood pressure at 30 minutes post exercise	30 minutes postexercsie	office blood pressure at 30 minutes post exercise

Secondary Outcome Measures

Name	Time	Method
daytime blood pressure	mean of 8 hours after the intervention	daytime ambulatory blood pressure (8 hours after the intervention)

Trial Locations

Locations (1)

Anton De Kom University; 🇸🇷 Paramaribo, Suriname