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Clinical Trials/NCT03988777
NCT03988777
Completed
Not Applicable

Magnetic Seed Localisation for Nonpalpable Breast Lesions: a Combined Retrospective and Prospective Analysis

Universitaire Ziekenhuizen KU Leuven1 site in 1 country192 target enrollmentSeptember 10, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Oncology
Sponsor
Universitaire Ziekenhuizen KU Leuven
Enrollment
192
Locations
1
Primary Endpoint
Number of participants with positive surgical margins as assessed by pathological examination of the specimen
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Screening programs and advances in imaging have led to more breast lesions being diagnosed at an impalpable stage. Multiple localisation techniques for nonpalpable breast lesions have been developed during the past decades. Specifically, several alternatives to the golden standard hooked-wire technique have become available, of which magnetic seed localisation is one of the newest approaches. Since September 2018, Magseed® localisation is the standard of care for localising impalpable breast lesions in UZ Leuven. In this study, the oncological safety, the clinical safety and surgeon satisfaction of Magseed® localisation will be assessed and retrospectively compared to hooked-wire localisation.

Registry
clinicaltrials.gov
Start Date
September 10, 2018
End Date
May 23, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Breast conserving surgery with preoperative localisation
  • Minimum 18 years old

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Number of participants with positive surgical margins as assessed by pathological examination of the specimen

Time Frame: Up to three weeks after surgical treatment

Re-operation rate due to positive surgical margins

Time Frame: Up to three weeks after surgical treatment

Surgeon satisfaction based on a questionnaire

Time Frame: After surgery

After surgery, the surgeon will be asked to describe the magnetic seed procedure, choosing between 'easier than hooked-wire' or 'more challenging than hooked-wire'. Moreover, the surgeon wil have the chance to add additional remarks or experiences with this new technique.

Number of participant with device-related adverse events

Time Frame: Up to three weeks after surgical treatment

Total breast volume resected during breast conserving surgery

Time Frame: Up to three weeks after surgical treatment

Study Sites (1)

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