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Clinical Trials/NCT03066596
NCT03066596
Completed
Not Applicable

Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination

Montefiore Medical Center1 site in 1 country530 target enrollmentMarch 7, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Asthma Childhood
Sponsor
Montefiore Medical Center
Enrollment
530
Locations
1
Primary Endpoint
Percentage of Participants With 1 or More Guideline-based Corrective Actions Taken
Status
Completed
Last Updated
6 months ago

Overview

Brief Summary

The overall goal of this research study is to test the effectiveness of a multifaceted and multi-level prompting intervention in a real world urban primary care office setting on improving provider-delivered guideline-based asthma care and reducing asthma morbidity among urban children with persistent or uncontrolled asthma.

Detailed Description

Investigators will conduct a cluster randomized trial comparing the intervention to enhanced usual care (eUC) in 20 Bronx practices serving over 5,000 children ages 2-12 years with persistent or uncontrolled asthma. Eleven eUC practices will receive guideline information and assess children's asthma severity and control, but active intervention components will not be provided. Practices will join the study in 4 waves over 4 years (4-6 practices per year). Provider adoption of guidelines and utilization of care in all patients (\~5,000) ages 2-12 years with persistent or uncontrolled asthma from intervention and eUC practices will be evaluated using Electronic Health Records (EHR) data and practice-based screening for asthma severity and control. Investigators will also enroll a random subset of 512 caregivers of children with persistent/uncontrolled asthma from both study arms to systematically evaluate caregiver-reported child morbidity outcomes and obtain measures not available in EHR. Intervention consists of academic detailing in the EHR that follow national asthma guidelines and outreach worker care coordination for patients with persistent or uncontrolled asthma. Comment: While caregivers reported on child outcomes, caregivers were not subjects of the study. See "Pre-Assignment Details" section within the Participant Flow module for more details.

Registry
clinicaltrials.gov
Start Date
March 7, 2017
End Date
August 24, 2024
Last Updated
6 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The criteria listed below will apply to \~5,000 children from eMPI and eUC practices:
  • Physician-diagnosed asthma (based on EHR)
  • Persistent or uncontrolled asthma as per clinic assessment. Based on NHLBI guidelines, any one of the following: in past month, \> 2 days/week with asthma symptoms, \>2 days/week with rescue medication use, \>2 days/month with nighttime symptoms, or \> 2 episodes in the past year that required systemic corticosteroids
  • Age 2 and 12 years, inclusive
  • Additional inclusion criteria will apply to a subset of 512 of children whose caregivers will be interviewed to obtain caregiver-reported morbidity outcomes:
  • Caregiver is able to speak and understand either English or Spanish. Participants unable to read will be eligible as all surveys will be administered verbally by research personnel
  • Consent from the primary caregiver, caregiver permission for the child to participate as well as assent from the child (\>7 years). If there are eligible siblings, only one child will be randomly selected

Exclusion Criteria

  • The child has other significant medical conditions, such as congenital heart disease, cystic fibrosis, or other chronic lung disease, that could interfere with the assessment of asthma-related measures
  • Additional exclusion criteria will apply to a subset of 512 children/caregivers as described above:
  • No access to a telephone to conduct follow-up surveys
  • Children in foster care or other situations in which consent cannot be obtained from a guardian

Outcomes

Primary Outcomes

Percentage of Participants With 1 or More Guideline-based Corrective Actions Taken

Time Frame: Immediately post-intervention, up to 1 year

The percentage of participants with 1 or more guideline-based corrective actions taken (i.e., controller medication prescription or adjustment, trigger evaluation), as recorded in the electronic health record (EHR) is reported. Results are summarized in number/percentage of participants with 1 or more guideline-based corrective actions taken by study arm.

Secondary Outcomes

  • Symptom Free Days (SFDs)(Baseline, and 3 month, 6 month, 9 month, and 12 month follow-up evaluations)

Study Sites (1)

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