Shortening Duration of Antiarrhythmic Medication for SVT in Infants

• Conditions: Supraventricular Tachycardia

• Registration Number: NCT04837261
• Lead Sponsor: Tampere University Hospital

Brief Summary

The infants diagnosed with SVT are treated with antiarrhythmic medication to prevent the recurrence of SVT. This prospective observational cohort study evaluates efficacy and safety of shortening duration of antiarrhythmic medication to four months in infants with SVT. Primary outcome is incidence of recurrent SVT in infants after 4 months of antiarrhythmic medication compared to retrospectively reviewed cohort.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-04-07
• Study First Submitted QC: 2021-04-07
• Study First Posted: 2021-04-08
• Study Start: 2021-04-15
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-28
• Last Update Posted: 2021-09-29
• Primary Completion: 2024-01-01
• Study Completion: 2024-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Age 6 months or less
• Documented SVT due to AVRT or AVNRT

Exclusion Criteria

• Age > 6 months
• Ectopic atrial tachycardia
• Atrial flutter
• Atrial fibrillation
• Permanent junctional reciprocating tachycardia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recurrence of SVT after antiarrhythmic medication	1 year follow-up

Secondary Outcome Measures

Name	Time	Method
Proportion of participants with treatment failure	4 months of antiarrhythmic medication
Prevalence of adverse events	4 months of antiarrhythmic medication
Recurrence of SVT after one year follow-up	5 year

Trial Locations

Locations (18)

Hämeenlinna Central Hospital; 🇫🇮 Hämeenlinna, Kanta-Häme, Finland

Sakunta Central Hospital; 🇫🇮 Pori, Satakunta, Finland

Central Finland Central Hospital; 🇫🇮 Jyväskylä, Central Finland, Finland

Kuopio University Hospital; 🇫🇮 Kuopio, North Savo, Finland

Kymenlaakso Central Hospital; 🇫🇮 Kotka, Region Of Kymenlaakso, Finland

Lapland Central Hospital; 🇫🇮 Rovaniemi, Lapland, Finland

Kokkola Central Hopsital; 🇫🇮 Kokkola, Central Ostrobothnia, Finland

Oulu University Hospital; 🇫🇮 Oulu, North Ostrobothnia, Finland

Kajaani Central Hospital; 🇫🇮 Kajaani, Kainuu, Finland

North Karelia Central Hospital; 🇫🇮 Joensuu, North Karelia, Finland

South Karelia Central Hospital; 🇫🇮 Lappeenranta, South Karelia, Finland

Vaasa Central Hospital; 🇫🇮 Vaasa, Ostrobothnia, Finland

Seinäjoki Central Hospital; 🇫🇮 Seinäjoki, South Ostrobothnia, Finland

Mikkeli Central Hospital; 🇫🇮 Mikkeli, South Savo, Finland

Helsinki University Hospital; 🇫🇮 Helsinki, Uusimaa, Finland

Turku University Hospital; 🇫🇮 Turku, Southwest, Finland

Tampere University Hospital; 🇫🇮 Tampere, Pirkanmaa, Finland

Lahti Central Hospital; 🇫🇮 Lahti, Päijät-Häme, Finland